Maximising adherence to study protocol within pharmaco-rehabilitation clinical trials
نویسندگان
چکیده
Background The Dopamine Augmented Rehabilitation in Stroke (DARS) trial is a double-blind placebo controlled trial investigating impact of co-careldopa/placebo in combination with routine NHS occupational/physical therapy on functional outcome in people with acute stroke. The trial involves participants taking Investigational Medicinal Product (IMP)/placebo prior to therapy sessions while in the acute stroke unit and following hospital discharge Stroke survivors may have significant residual impairments such as weakness, aphasia, visual disturbance, cognitive problems and mood disorders which may affect their ability to comply with DARS medication/ therapy schedule.
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